Huge sections of the human genome are made up of highly repetitive sequences, areas where bases like ATATAT repeat in very long strings. For many years, scientists wrote these repetitive sequences off ...
A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.
Inactivation of mismatch repair (MMR) causes inherited and sporadic cancers 1. These tumours exhibit microsatellite instability (MSI) - length alterations within short repeats. MSI is a diagnostic and ...
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell’s own machinery to achieve its goals. In a new work appearing online Wednesday in ...
Since the 1990s, nanopores have been used for sequencing strands of DNA. A voltage is applied across the nanopore, which is embedded in a thin lipid membrane, causing a stretch of DNA to thread ...
Scientists have found that non-coding 'junk' DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the ...
Like their viral cousins, retrotransposons have been found borrowing the cell's own machinery to achieve their goals. They hijack a little-known piece of the cell's DNA repair function to close ...
Zettabytes—that’s 10 21 bytes—of data are currently generated every year. All of those cat videos have to be stored somewhere, and DNA is a great storage medium; it has amazing data density and is ...